Abstract
A kind of useful precursors for the construction of vicinal diaryl-substituted macrocycles, 4,5-diaryl-1,8-dihalo-3,6-dioxaoctanes, was readily produced by reductive coupling of aromatic carbonyl compounds with 2-haloethanols in the presence of tin powder and chlorotrimethylsilane in moderate to good yields by a one-pot procedure.