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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 30, 2000 - Issue 19
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Original Articles

An Improved Synthesis of 5-Fluorothiophene-2-Carboxylic Acid

Robert J. Chambers Pfizer Central Research, Groton, CT, 06340
&
Anthony Marfat Pfizer Central Research, Groton, CT, 06340
Pages 3629-3632 | Received 15 Jan 2000, Published online: 04 Dec 2007
 
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Abstract

A new and efficient route to 5-fluorothiophene-2-carboxylic acid 1 was secured in two steps and 62% yield overall.

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