Palladium-Catalyzed Coupling Reaction of Iodouracil Having Acetamidine Moiety with Olefins

Young Hae Roh Biochemicals Research Center, Korea Institute of Science and Technology, P. O. Box 131, Cheongryang, Seoul, Korea

Jong Woo Bae Department of Life Science & Biotechnology, Graduate school of Biotechnology, Korea University, Sungbookgu Anamdong 5 ga 126--16, Seoul, Korea

Gil Soo Nam Biochemicals Research Center, Korea Institute of Science and Technology, P. O. Box 131, Cheongryang, Seoul, Korea

Joong Hyup Kim Biochemicals Research Center, Korea Institute of Science and Technology, P. O. Box 131, Cheongryang, Seoul, Korea

Sung Hoon Kim Biochemicals Research Center, Korea Institute of Science and Technology, P. O. Box 131, Cheongryang, Seoul, Korea

Cheol Min Yoon Department of Life Science & Biotechnology, Graduate school of Biotechnology, Korea University, Sungbookgu Anamdong 5 ga 126--16, Seoul, Korea

Abstract

The reaction of 6-[1-Aza-2-(dimethylamino)prop-l-enyl]-5-iodo-1,3-dimethyluracil (3) with various olefins in the presence of a catalytic amount of Pd(OAc)₂ and 1.5 equiv. of K₂CO₃ in DMF at 120 °C gave the pyrido[2,3-d]pyrimidine derivatives (5a-b and 7a-d) in moderate to high yield.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Palladium-Catalyzed Coupling Reaction of Iodouracil Having Acetamidine Moiety with Olefins

Information for

Open access

Opportunities

Help and information

Palladium-Catalyzed Coupling Reaction of Iodouracil Having Acetamidine Moiety with Olefins

Abstract

Reprints and Corporate Permissions

Academic Permissions

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date

Your download is now in progress and you may close this window

Login or register to access this feature