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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 30, 2000 - Issue 4
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Original Articles

One-Step Gem-Diphosphorylation of Amides and Lactams

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Pages 619-627 | Received 30 Apr 1999, Accepted 18 Jun 1999, Published online: 04 Dec 2007
 

Abstract

We report the extension of an easy one-step synthesis of amino gem-bisphosphonates through the reaction of amides and lactams with trialkylphosphites.

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