Conversion of Epoxides to β‐Chlorohydrins with Thionyl Chloride and β‐Cyclodextrin in Water

Abstract

Several epoxides are efficiently converted to the corresponding β‐chlorohydrins in impressive yields with thionyl chloride in the presence of β‐cyclodextrin using water as solvent at room temperature.

Keywords:

• β‐Chlorohydrins
• β‐cyclodextrin
• epoxides
• thionyl chloride
• water

Acknowledgment

K.S. thanks Council of Scientific Research (CSIR), New Delhi, India, for the award of a research fellowship. IICT Communication No. 040911.