Sodium Borohydride–Solid LiClO₄: An Effective Reagent for Reducing Aldehydes and Ketones in Aprotic Solvent

Abstract

An efficient and simple method for the reduction of aldehydes, ketones and acid chlorides has been accomplished by using NaBH₄–solid LiClO₄ in mild conditions at ambient temperature with complete chemoselectivity in reduction of α,β‐unsaturated aldehydes and ketones. The reaction is fast with high yield and simple workup.

Keywords:

• Lithium perchlorate
• reduction
• sodium borohydride

Acknowledgments

We are grateful to the research council of Sharif University for financial support.