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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 35, 2005 - Issue 17
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Original Articles

First Example of Transition‐Metal‐Free Glaser‐Type Coupling Reaction

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Pages 2333-2338 | Received 28 Feb 2005, Published online: 18 Aug 2006
 

Abstract

In the presence of potassium tert‐butoxide and in toluene, 1,1‐dibromo‐1‐alkenes smoothly generated the corresponding Glaser‐type coupling‐reaction products (1,3‐diynes) in moderate to good yields.

Acknowledgments

We gratefully acknowledge financial support by the National Natural Science Foundation of China (No. 20372024); the Excellent Scientist Foundation of Anhui Province, China (No. 04046080); the Natural Science Foundation of the Education Department of Anhui Province, China (No. 2002kj254zd); the Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry, China (No. 2002247); the Excellent Young Teachers Program of MOE, China (No. 2024); and the Key Project of Science and Technology of State Education Ministry, China (No. 0204069).

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