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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 35, 2005 - Issue 23
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Original Articles

Organic Reactions in Ionic Liquids: Ionic Liquid Ethylammonium Nitrate–Promoted Knoevenagel Condensation of Meldrum's Acid With Aromatic Aldehydes

Yi Hu College of Life Science and Pharmaceutical Engineering, Nanjing University of Technology, Nanjing, China; Department of Chemistry, Zhejiang University (Xi Xi Campus), Hangzhou, ChinaCorrespondence[email protected]
,
Ping Wei College of Life Science and Pharmaceutical Engineering, Nanjing University of Technology, Nanjing, China
,
He Huang College of Life Science and Pharmaceutical Engineering, Nanjing University of Technology, Nanjing, China
,
Zhang‐Gao Le Department of Applied Chemistry, East China Institute of Technology, Fuzhou, China
&
Zhen‐Chu Chen Department of Chemistry, Zhejiang University (Xi Xi Campus), Hangzhou, China
Pages 2955-2960 | Received 27 Mar 2005, Published online: 21 Aug 2006
 
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Abstract

The Knoevenagel condensation of Meldrum's acid with aromatic aldehydes proceeded efficiently in a reusable ionic liquid, ethylammonium nitrate, at room temperature in the absence of any catalyst with high yields.

Acknowledgments

This work is supported by the Natural Sciences Foundation of China (No: 20336010), and the State Key Basic Research and Development Project of China (No: 2003CB7160004).

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