N‐Methylpiperidine—A Useful Base Catalyst in the Morita–Baylis–Hillman Reaction

Abstract

N‐methylpiperidine, a commercially available mild base, has effectively been utilized as a catalyst in the Morita–Baylis–Hillman reaction. Moderate to excellent yields (34–95%) and significant rate enhancement have been observed.

Keywords:

• Aldehyde
• base catalyst
• Morita–Baylis–Hillman reaction
• dioxane–water
• N‐methylpiperidine

Acknowledgments

This work was supported by the Natural Science Foundation of China (No. 30000112), the Laboratory of Organic Solids, Chinese Academy of Sciences, and the Science Foundation of Taiyuan City of China; we are grateful to them.