First Synthesis of N‐Substituted Amino and N‐Sulfonylaminated Methylthiopyrimidines: Reaction of Dimethyl N‐Cyanodithioiminocarbonate With Substituted Hydrazides

Abstract

A novel and efficient method for the synthesis of a new variety of methylsulfanylpyrimidines by the reaction of dimethyl N‐cyanodithioiminocarbonate with substituted hydrazides. The synthetic potential of the method is demonstrated.

Keywords:

• Antimetabolites
• cyanoacetohydrazide
• dimethyl N‐cyanodithioiminocarbonate
• heterocycles
• methylsulfanylpyrimidines
• substituted hydrazides