Abstract
Aminosulfonic acid is an environmentally friendly catalyst. Grinding a mixture of aromatic aldehydes, barbituric acid, and H2NSO3H at room temperature (without any solvent) gave 5‐arylidene barbituric acid in high yields, providing a simple and efficient route to synthesis of these compounds.
Acknowledgments
Educational Ministry of China, Educational Department of Hebei Province (2001104), and Natural Science Foundation of Hebei Province (203107), China, supported the project.