Abstract
Graphical Abstract Section
Abstract
Synth. Commun. 2006, 35, 685
Synthesis and Mesogenic Properties of Novel Terthiophene Derivatives
Ping Liu,1 Miaomiao Liu,1 and Wenji Deng2
1Research Institute of Materials Science, South China University of Technology, Guangzhou, China
2Department of Applied Physics, South China University of Technology, Guangzhou, China.
Abstract
Synth. Commun. 2006, 35, 693
Concise Synthesis of the Angular Dihydrofuroquinoline Alkaloids via Cyclopropane Opening in the Presence of Polyphosphoric Acid
Jiangtao Su, Juan Xiong, Shucai Liang, Guofu Qiu, Xichun Feng, Hanbing Teng, Lamei Wu, and Xianming Hu
State Key Laboratory of Virology, College of Pharmacy, Wuhan University, Wuhan, China
A concise method for synthesis of dihydrofuroquinolinone alkaloids was reported, which the cyclopropane opening and closure was the key step. The only angluar type product was obtained in fair yields. A possible mechanism in also described.
Abstract
Synth. Commun. 2006, 35, 701
Synthesis and Fluorescence of N,N,N‐Trimethyl‐2‐[methyl(7‐nitrobenzo[c][l,2,5]oxadiazol‐4‐yl) amino]ethanaminium Iodide, a pH‐Insensitive Reporter of Organic Cation Transport
Bhasker Reddy Aavula,1 M. Ahad Ali,1 Eugene A. Mash,1 Dallas Bednarczyk,2 and Stephen H. Wright2
1Departments of Chemistry and 2Physiology, University of Arizona, Tucson, Arizona, USA.
Abstract
Synth. Commun. 2006, 35, 707
New bis‐Pyrazole Derivatives Synthesized from Aryl‐ and Xylyl‐Linked bis(β‐Diketone) Precursors
Michael J. Hayter, David J. Bray, Jack K. Clegg, and Leonard F. Lindoy
Centre for Heavy Metals Research, School of Chemistry, University of Sydney, N.S.W., Australia
The synthesis and characterization of six new aryl‐linked, and in one instance xylyl‐linked, bis‐pyrazoles are reported. The X‐ray structures of two of these derivatives are also presented.
Abstract
Synth. Commun. 2006, 35, 715
Diarylimidoylcyanides, an Attractive Class of Intermediate: Novel Synthesis of α‐Anilino‐β‐Nitroenamines, N, N′‐ Disubstituted Amidines and Substituted Phenyl Glyoxate
Abhijit Roychowdhury, Versha V. Kumar, and A. P. Bhaduri
Medicinal Chemistry Division, Central Drug Research Institute, Lucknow, India
Abstract
Synth. Commun. 2006, 35, 729
Synthesis of New 1,2,4- and 1,3,4-Oxadiazole Derivatives as Potential Nonpeptide Angiotensin II Receptor Antagonists
Emerson Meyer,1 Antonio C. Joussef2, and Luciana de B. P. de Souza2
1Departamento de Química Orgânica e Inorgânica, Universidade Federal do Ceará, Fortaleza, Brazil
2Departamento de Química, Universidade Federal de Santa Catarina, Florianópolis, Brazil
The synthesis of new potential nonpeptide angiotensin II receptor antagonists is presented. The alkylation reactions of 3-alkylquinoxalinones were performed under PTC conditions with good yields and high N/O ratios.
Abstract
Synth. Commun. 2006, 35, 743
First Synthesis of N-Substituted amino and N-Sulfonylaminated Methylthiopyrimidines: Reaction of Dimethyl N-Cyanodithioiminocarbonate with Substituted Hydrazides
Galal H. Elgemeie and Soha A. Sood
Chemistry Department, Faculty of Science, Helwan University, Ain-Helwan, Cairo, Egypt
A novel and efficient method for the synthesis of a new variety of methylsulfanylpyrimidines by the reaction of dimethyl N-cyanodithioiminocarbonate with substituted hydrazides. The synthetic potential of the method is demonstrated.
Abstract
Synth. Commun. 2006, 35, 755
Novel 1,3-Dithiolan-2-ones using Sodium α-Cyanoketene Dithiolates
G. H. Elgemeie,1 A. H. Elghandour,2 A. M. Elzanaty,2 and S. A. Ahmed2
1Department of Chemistry, Faculty of Science, Helwan University, Ain-Helwan, Cairo, Egypt
2Department of Chemistry, Faculty of Science, Cairo University (Bani Suef Branch), Bani Suef, Egypt
A novel and efficient method for the synthesis of 1,3-dithiolan-2-ones using sodium α-cyanoketene dithiolates and monochloroacetic acid as starting components is described.
Abstract
Synth. Commun. 2006, 35, 765
Reduction of 3-Acyl Derivatives of Oxindoles, Benzo[B]Furan-2-ones, and Benzo[B]thiophen-2-ones to the Corresponding Alkyl Derivatives by Sodium Borohydride–Acetic Acid
Francis X. Smith, Brian D. Williams, Eric Gelsleichter, Judy A. Podcasy, John T. Sisko, and David M. Hrubowchak
Department of Chemistry, King's College, Wilkes-Barre, Pennsylvania, USA
It was found that 3-acyl derivatives of oxindoles, benzo[b]furan-2-ones, and benzo[b]thiophen-2-ones could be efficiently and conveniently reduced to the corresponding alkyl derivatives by pelletized sodium borohydride in acetic acid.
Abstract
Synth. Commun. 2006, 35, 771
Synthesis of 2‐Spironaphtho[2,3‐b]pyranoquinones
Ricardo A. Tapia, Angela Bau, and Cristian Salas
Facultad de Química, Pontificia Universidad Católica de Chile, Santiago, Chile
A convenient procedure for the synthesis of 2-spirobenzopyranoquinone 5 and its application to the preparation of spironaphtho[2,3,‐b]pyranoquinones 6 and 7 is described.
Abstract
Synth. Commun. 2006, 35, 777
Efficient α-Chlorination of Aryl Ketones using Aluminum Chloride/Urea–Hydrogen Peroxide in Ionic Liquid
Jong Chan Lee and Hyun Jung Park
Department of Chemistry, Chung-Ang University, Seoul, South Korea
A new method is developed for the conversion of aryl ketones into their corresponding α-chloroketones with AlCl3/UHP in [bmim]BF4.
Abstract
Synth. Commun. 2006, 35, 781
Synthesis of Novel Murrapanine analogues by Microwave Irradiation
Xiaohe Guo,1 Weidong Hu,2 Senxiang Cheng,2 Li-Min Wang,2 and Junbiao Chang1,2
1Department of Chemistry, University of Science and Technology of China, Hefei, China
2Henan Key Laboratory of Fine Chemicals, Zhengzhou, China
Some new Murrapanine analogues have been synthesized via microwave irradiation by intermolecular Diels–Alder cyclization of 1-tosyl-3-(3-methyl-1,3-vinylallyl) indole with a dienophile such as quinone.
Abstract
Synth. Commun. 2006, 35, 789
Efficient Method for Synthesis of the Derivatives of 5-Arylidene Barbituric Acid Catalyzed by Aminosulfonic Acid with Grinding
Ji-Tai Li, Hong-Guang Dai, Da Liu, and Tong-Shuang Li
College of Chemistry and Environmental Science, Hebei University, Key Laboratory of Analytical Science and Technology of Hebei Province, Baoding, China
Aminosulfonic acid is an environmentally friendly catalyst. Grinding a mixture of benzaldehydes, barbituric acid, and H2NSO3H at room temperature (without any solvent) gave 5-arylidene barbituric acid in high yields, providing a simple and efficient route to synthesis of these compounds.
Abstract
Synth. Commun. 2006, 35, 795
Zirconium(IV) Chloride–Mediated Chemoselective Conjugate Addition of Aliphatic Amines to α,β-Ethylenic Compounds
H. M. Meshram, C. Lakshindra, P. N. Reddy, K. Sadashiv, and J. S. Yadav
Organic Chemistry-1, Indian Institute of Chemical Technology, Hyderabad, India
Abstract
Synth. Commun. 2006, 35, 803
SbCl3-Al2O3–Catalyzed, Solvent-Free, One-Pot Synthesis of Benzo[b]1,4-diazepines
Bilal A. Ganai, Satish Kumar, Charanjeet S. Andotra, and Kamal K. Kapoor
Department of Chemistry, University of Jammu, Jammu, India
Abstract
Synth. Commun. 2006, 35, 809
Synthesis of Potentially Bioactive Heterocycles: Thermal [3,3] Sigmatropic Rearrangement of 4-(4′-Aryloxybut-2′-Ynyloxy)-6-methyl-2-pyridone
K. C. Majumdar, H. Rahaman, and B. Roy
Department of Chemistry, University of Kalyani, Kalyani, India
Two-step formation of the exocyclic olefinic compounds from corresponding pyridones ethers.
Abstract
Synth. Commun. 2006, 35, 817
Neat Reaction Technology for the Synthesis of Novel 1,5-Benzodiazepines
Mazaahir Kidwai and Poonam Mothsra
Department of Chemistry, University of Delhi, Delhi, India
A convenient, solvent-free, green approach is described for the synthesis of novel 1,5-benzodiazepines by the reaction of ethylacetoacetate, aldehyde, and o-phenylenediamine without any catalyst at pH 7.
Abstract
Synth. Commun. 2006, 35, 825
Novel Alkylsulfanylisothiazoles and Alkylsulfanylthiophens using Sodium α-Cyanoketene Dithiolates as Starting Materials
G. H. Elgemeie,1 A. M. Elzanaty,2 A. H. Elghandour,2 and S. A. Ahmed2
1Department of Chemistry, Faculty of Science, Helwan University, Helwan, Cairo, Egypt
2Department of Chemistry, Faculty of Science, Cairo University (Bani Suef Branch), Bani Suef, Egypt
A novel and efficient method for the synthesis of alkylsulfanylisothiazoles and alkylsulfanylthiophenes using sodium α-cyanoketene dithiolates as starting components is described.