Graphical Abstracts

Abstract

Graphical Abstract Section

Abstract

Synth. Commun. 2006, 35, 685

Synthesis and Mesogenic Properties of Novel Terthiophene Derivatives

Ping Liu,¹ Miaomiao Liu,¹ and Wenji Deng²

¹Research Institute of Materials Science, South China University of Technology, Guangzhou, China

²Department of Applied Physics, South China University of Technology, Guangzhou, China.

Abstract

Synth. Commun. 2006, 35, 693

Concise Synthesis of the Angular Dihydrofuroquinoline Alkaloids via Cyclopropane Opening in the Presence of Polyphosphoric Acid

Jiangtao Su, Juan Xiong, Shucai Liang, Guofu Qiu, Xichun Feng, Hanbing Teng, Lamei Wu, and Xianming Hu

State Key Laboratory of Virology, College of Pharmacy, Wuhan University, Wuhan, China

A concise method for synthesis of dihydrofuroquinolinone alkaloids was reported, which the cyclopropane opening and closure was the key step. The only angluar type product was obtained in fair yields. A possible mechanism in also described.

Abstract

Synth. Commun. 2006, 35, 701

Synthesis and Fluorescence of N,N,N‐Trimethyl‐2‐[methyl(7‐nitrobenzo[c][l,2,5]oxadiazol‐4‐yl) amino]ethanaminium Iodide, a pH‐Insensitive Reporter of Organic Cation Transport

Bhasker Reddy Aavula,¹ M. Ahad Ali,¹ Eugene A. Mash,¹ Dallas Bednarczyk,² and Stephen H. Wright²

¹Departments of Chemistry and ²Physiology, University of Arizona, Tucson, Arizona, USA.

Abstract

Synth. Commun. 2006, 35, 707

New bis‐Pyrazole Derivatives Synthesized from Aryl‐ and Xylyl‐Linked bis(β‐Diketone) Precursors

Michael J. Hayter, David J. Bray, Jack K. Clegg, and Leonard F. Lindoy

Centre for Heavy Metals Research, School of Chemistry, University of Sydney, N.S.W., Australia

The synthesis and characterization of six new aryl‐linked, and in one instance xylyl‐linked, bis‐pyrazoles are reported. The X‐ray structures of two of these derivatives are also presented.

Abstract

Synth. Commun. 2006, 35, 715

Diarylimidoylcyanides, an Attractive Class of Intermediate: Novel Synthesis of α‐Anilino‐β‐Nitroenamines, N, N′‐ Disubstituted Amidines and Substituted Phenyl Glyoxate

Abhijit Roychowdhury, Versha V. Kumar, and A. P. Bhaduri

Medicinal Chemistry Division, Central Drug Research Institute, Lucknow, India

Abstract

Synth. Commun. 2006, 35, 729

Synthesis of New 1,2,4- and 1,3,4-Oxadiazole Derivatives as Potential Nonpeptide Angiotensin II Receptor Antagonists

Emerson Meyer,¹ Antonio C. Joussef², and Luciana de B. P. de Souza²

¹Departamento de Química Orgânica e Inorgânica, Universidade Federal do Ceará, Fortaleza, Brazil

²Departamento de Química, Universidade Federal de Santa Catarina, Florianópolis, Brazil

The synthesis of new potential nonpeptide angiotensin II receptor antagonists is presented. The alkylation reactions of 3-alkylquinoxalinones were performed under PTC conditions with good yields and high N/O ratios.

Abstract

Synth. Commun. 2006, 35, 743

First Synthesis of N-Substituted amino and N-Sulfonylaminated Methylthiopyrimidines: Reaction of Dimethyl N-Cyanodithioiminocarbonate with Substituted Hydrazides

Galal H. Elgemeie and Soha A. Sood

Chemistry Department, Faculty of Science, Helwan University, Ain-Helwan, Cairo, Egypt

A novel and efficient method for the synthesis of a new variety of methylsulfanylpyrimidines by the reaction of dimethyl N-cyanodithioiminocarbonate with substituted hydrazides. The synthetic potential of the method is demonstrated.

Abstract

Synth. Commun. 2006, 35, 755

Novel 1,3-Dithiolan-2-ones using Sodium α-Cyanoketene Dithiolates

G. H. Elgemeie,¹ A. H. Elghandour,² A. M. Elzanaty,² and S. A. Ahmed²

¹Department of Chemistry, Faculty of Science, Helwan University, Ain-Helwan, Cairo, Egypt

²Department of Chemistry, Faculty of Science, Cairo University (Bani Suef Branch), Bani Suef, Egypt

A novel and efficient method for the synthesis of 1,3-dithiolan-2-ones using sodium α-cyanoketene dithiolates and monochloroacetic acid as starting components is described.

Abstract

Synth. Commun. 2006, 35, 765

Reduction of 3-Acyl Derivatives of Oxindoles, Benzo[B]Furan-2-ones, and Benzo[B]thiophen-2-ones to the Corresponding Alkyl Derivatives by Sodium Borohydride–Acetic Acid

Francis X. Smith, Brian D. Williams, Eric Gelsleichter, Judy A. Podcasy, John T. Sisko, and David M. Hrubowchak

Department of Chemistry, King's College, Wilkes-Barre, Pennsylvania, USA

It was found that 3-acyl derivatives of oxindoles, benzo[b]furan-2-ones, and benzo[b]thiophen-2-ones could be efficiently and conveniently reduced to the corresponding alkyl derivatives by pelletized sodium borohydride in acetic acid.

Abstract

Synth. Commun. 2006, 35, 771

Synthesis of 2‐Spironaphtho[2,3‐b]pyranoquinones

Ricardo A. Tapia, Angela Bau, and Cristian Salas

Facultad de Química, Pontificia Universidad Católica de Chile, Santiago, Chile

A convenient procedure for the synthesis of 2-spirobenzopyranoquinone 5 and its application to the preparation of spironaphtho[2,3,‐b]pyranoquinones 6 and 7 is described.

Abstract

Synth. Commun. 2006, 35, 777

Efficient α-Chlorination of Aryl Ketones using Aluminum Chloride/Urea–Hydrogen Peroxide in Ionic Liquid

Jong Chan Lee and Hyun Jung Park

Department of Chemistry, Chung-Ang University, Seoul, South Korea

A new method is developed for the conversion of aryl ketones into their corresponding α-chloroketones with AlCl₃/UHP in [bmim]BF₄.

Abstract

Synth. Commun. 2006, 35, 781

Synthesis of Novel Murrapanine analogues by Microwave Irradiation

Xiaohe Guo,¹ Weidong Hu,² Senxiang Cheng,² Li-Min Wang,² and Junbiao Chang^1,2

¹Department of Chemistry, University of Science and Technology of China, Hefei, China

²Henan Key Laboratory of Fine Chemicals, Zhengzhou, China

Some new Murrapanine analogues have been synthesized via microwave irradiation by intermolecular Diels–Alder cyclization of 1-tosyl-3-(3-methyl-1,3-vinylallyl) indole with a dienophile such as quinone.

Abstract

Synth. Commun. 2006, 35, 789

Efficient Method for Synthesis of the Derivatives of 5-Arylidene Barbituric Acid Catalyzed by Aminosulfonic Acid with Grinding

Ji-Tai Li, Hong-Guang Dai, Da Liu, and Tong-Shuang Li

College of Chemistry and Environmental Science, Hebei University, Key Laboratory of Analytical Science and Technology of Hebei Province, Baoding, China

Aminosulfonic acid is an environmentally friendly catalyst. Grinding a mixture of benzaldehydes, barbituric acid, and H₂NSO₃H at room temperature (without any solvent) gave 5-arylidene barbituric acid in high yields, providing a simple and efficient route to synthesis of these compounds.

Abstract

Synth. Commun. 2006, 35, 795

Zirconium(IV) Chloride–Mediated Chemoselective Conjugate Addition of Aliphatic Amines to α,β-Ethylenic Compounds

H. M. Meshram, C. Lakshindra, P. N. Reddy, K. Sadashiv, and J. S. Yadav

Organic Chemistry-1, Indian Institute of Chemical Technology, Hyderabad, India

Abstract

Synth. Commun. 2006, 35, 803

SbCl₃-Al₂O₃–Catalyzed, Solvent-Free, One-Pot Synthesis of Benzo[b]1,4-diazepines

Bilal A. Ganai, Satish Kumar, Charanjeet S. Andotra, and Kamal K. Kapoor

Department of Chemistry, University of Jammu, Jammu, India

Abstract

Synth. Commun. 2006, 35, 809

Synthesis of Potentially Bioactive Heterocycles: Thermal [3,3] Sigmatropic Rearrangement of 4-(4′-Aryloxybut-2′-Ynyloxy)-6-methyl-2-pyridone

K. C. Majumdar, H. Rahaman, and B. Roy

Department of Chemistry, University of Kalyani, Kalyani, India

Two-step formation of the exocyclic olefinic compounds from corresponding pyridones ethers.

Abstract

Synth. Commun. 2006, 35, 817

Neat Reaction Technology for the Synthesis of Novel 1,5-Benzodiazepines

Mazaahir Kidwai and Poonam Mothsra

Department of Chemistry, University of Delhi, Delhi, India

A convenient, solvent-free, green approach is described for the synthesis of novel 1,5-benzodiazepines by the reaction of ethylacetoacetate, aldehyde, and o-phenylenediamine without any catalyst at pH 7.

Abstract

Synth. Commun. 2006, 35, 825

Novel Alkylsulfanylisothiazoles and Alkylsulfanylthiophens using Sodium α-Cyanoketene Dithiolates as Starting Materials

G. H. Elgemeie,¹ A. M. Elzanaty,² A. H. Elghandour,² and S. A. Ahmed²

¹Department of Chemistry, Faculty of Science, Helwan University, Helwan, Cairo, Egypt

²Department of Chemistry, Faculty of Science, Cairo University (Bani Suef Branch), Bani Suef, Egypt

A novel and efficient method for the synthesis of alkylsulfanylisothiazoles and alkylsulfanylthiophenes using sodium α-cyanoketene dithiolates as starting components is described.