Exclusive Formation of 1‐Aryl‐3‐(5‐nitro‐2‐furyl)‐4‐aroylpyrazoles via Regiospecific 1,3‐Dipolar Cycloaddition of 3‐Arylsydnones with α,β‐Acetylenic Ketones

Abstract

1,3‐Dipolar cycloaddition of 3‐arylsydnones with α,β‐acetylenic ketones containing nitrofuran moiety has been studied, and it was observed that the dipolar cycloaddition is regiospecific, forming 1‐aryl‐3‐(5‐nitro‐2‐furyl)‐4‐aroylpyrazoles exclusively.

Keywords:

• 1,3‐Dipolar addition
• pyrazoles
• regiospecific reaction
• sydnones

Acknowledgments

The authors thank Head, Regional Sophisticated Instrumentation Centre (RSIC), Chandigarh, and Central Drug Research Institute (CDRI), Lucknow, for spectral and analytical data. The authors are also thankful to University Grants Commission (UGC), New Delhi, for the financial assistance.