Zinc Hydroxyapatite–Catalyzed Efficient Synthesis of 5‐Substituted 1H‐Tetrazoles

Abstract

Zinc hydroxyapatite (ZnHAP) is an effective heterogeneous catalyst for the (2+3)‐cycloaddition of sodium azide with nitriles to afford 5‐substituted 1H‐tetrazoles in good yields. The catalyst is recovered and reused for several cycles with consistent activity.

Keywords:

• (2+3)‐Cycloaddition
• heterogeneous catalyst
• 5‐substituted 1H‐tetrazoles
• zinc hydroxyapatite

Acknowledgment

We thank the CSIR for financial support under the Task Force Project CMM‐0006. K. B. Shiva Kumar thanks UGC, India, for the fellowship.