One‐Step Synthesis of Aromatic Terminal Alkynes from Their Corresponding Ketones under Microwave Irradiation

Abstract

One‐step microwave‐assisted synthesis of phenylacetylenes 2a–j from the corresponding ketones 1a–j in the presence of a new reagent, PCl₅–pyridine, is described. The reaction is carried out under a simple operational and experimental procedure, avoiding the use of the complicated and harsh multistep reaction.

Keywords:

• Microwave activation
• One‐step synthesis
• PCl₅–pyridine reagent
• Phenylacetylene derivatives