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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 36, 2006 - Issue 21
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Original Articles

Efficient Synthesis of β‐Amino Alcohols Catalyzed by Niobium Pentachloride: Regioselective Ring Opening of Epoxides with Aromatic Amines

, &
Pages 3183-3189 | Received 12 Apr 2006, Published online: 24 Nov 2006
 

Abstract

Epoxides undergo a rapid ring‐opening reaction with aromatic amines catalyzed by niobium pentachloride under mild reaction conditions. All the reactions were carried out at room temperature to afford the corresponding β‐amino alcohols in excellent yields and with high regioselectivity.

IICT Communication No. 050916

Acknowledgment

D. S. thanks Council of Scientific & Industrial Research (CSIR), New Delhi, for providing a fellowship.

Notes

IICT Communication No. 050916

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