Mild and Efficient Solvent‐Free Friedel–Crafts Acylation of Reserpine

Sabira Begum H.E.J. Research Institute of Chemistry, International Center for Chemical Sciences, University of Karachi, Karachi, PakistanCorrespondence[email protected]

Syeda Qamar Zehra H.E.J. Research Institute of Chemistry, International Center for Chemical Sciences, University of Karachi, Karachi, Pakistan

Bina S. Siddiqui H.E.J. Research Institute of Chemistry, International Center for Chemical Sciences, University of Karachi, Karachi, Pakistan

Abstract

The first mild, efficient, solvent‐free Friedel–Crafts acylation of reserpine has been developed, which resulted in the synthesis of 10‐ and 12‐acylated homologues in high overall yields.

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Mild and Efficient Solvent‐Free Friedel–Crafts Acylation of Reserpine

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Mild and Efficient Solvent‐Free Friedel–Crafts Acylation of Reserpine

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