One‐Pot Synthesis of Oxime Derivatives of 1,3‐Diphenylpyrazole‐4‐carboxaldehydes from Acetophenone Phenylhydrazones Using Vilsmeier–Haack Reagent

Abstract

A one‐pot synthesis of oxime derivatives 3a–3f of 1‐phenyl‐3‐arylpyrazole‐4‐carboxaldehydes has been accomplished by the Vilsmeier–Haack reaction of acetophenone phenylhydrazones 1a–1f under a new workup procedure.

Keywords:

• Vilsmeier‐Haack reaction
• acetophenone phenylhydrazones
• 1,3‐diphenylpyrazole‐4‐carboxaldehydes
• hydroxylamine
• 1,3‐diphenylpyrazole‐4‐carboxaldehyde oximes

Acknowledgment

We are thankful to Defense Research & Development Organisation (DRDO) (ERIP/ER/0303447/M/01), New Delhi, India, for financial support to carry out the work described.