Efficient and Mild Procedure for Reductive Methylation of Amines Using N‐Methylpiperidine Zinc Borohydride

Heshmatollah Alinezhad Department of Chemistry, Mazandaran University, Babolsar, IranCorrespondence[email protected]

Mahmood Tajbakhsh Department of Chemistry, Mazandaran University, Babolsar, Iran

Reza Zamani Department of Chemistry, Mazandaran University, Babolsar, Iran

Abstract

A simple and efficient procedure for reductive methylation of primary and secondary amines using N‐methylpiperidine zinc borohydride (ZBNMPP), giving tertiary amines, is described. The reaction is carried out in methanol at room temperature under neutral conditions.

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Acknowledgment

Financial support of this work from the Research Council of Mazandaran University is gratefully acknowledged.

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Efficient and Mild Procedure for Reductive Methylation of Amines Using N‐Methylpiperidine Zinc Borohydride

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Efficient and Mild Procedure for Reductive Methylation of Amines Using N‐Methylpiperidine Zinc Borohydride

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