Facile Solid‐Phase Synthesis of Cycloalkylphosphonates and 1‐Cycloalkenylphosphonates Using Polymer‐Supported Phenylsulfonylmethylphosphonates

Abstract

A facile procedure for the solid‐phase synthesis of cycloalkylphosphonates and 1‐cycloalkenylphosphonates in good yields and high purities using polystyrene‐supported phenylsulfonylmethylphosphonates with traceless sulfone linker strategy is described.

Keywords:

• 1‐cycloalkenylphosphonate
• cycloalkylphosphonate
• polymer‐supported phenylsulfonylmethylphosphonate
• solid‐phase organic synthesis

Acknowledgment

We gratefully acknowledge financial support from the National Natural Science Foundation of China (No. 20562005) and Natural Science Foundation of Jiangxi Province.