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Abstract
Graphical Abstract Section
Abstract
Synth. Commun. 2007, 37, 361
FACILE TOTAL SYNTHESIS OF XANTHOTOXOL
Wei He,1 Bang-Le Zhang,2 Si-Yuan Zhou,2 Xiao-Li Sun,1 Sheng-Yong Zhang1
1Department of Chemistry, Fourth Military Medical University, Xi'an, Shaanxi, China
2Department of Pharmacology, Fourth Military Medical University, Xi'an, Shaanxi, China
Abstract
Synth. Commun. 2007, 37, 369
IMPROVED SYNTHESIS OF 2-(3H)BENZOTHIAZOLETHIONES UNDER MICROWAVE IRRADIATION
Wei Huang, Ying Tan, Ming-Wu Ding, and Guang-Fu Yang
Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Wuhan, China
Abstract
Synth. Commun. 2007, 37, 377
REACTION OF IMIDAZO[1,2-A]PYRIDINES WITH ALIPHATIC ALDEHYDES: A SIMPLE AND EFFICIENT METHOD FOR THE PREPARATION OF NOVEL C-3 VINYLIC DERIVATIVES OF IMIDAZO[1,2-A]PYRIDINES
Rui Zhang and Yongzhou Hu
Ecole Normal Superieure Joint Laboratory of Medicinal Chemistry, School of Pharmaceutical Sciences, Zhejiang University, Zijingang Campus, Hangzhou, P.R. China
A number of C-3 vinylic derivatives of imidazo[1,2-a]pyridines were synthesized by the reaction of imidazo[1,2-a]pyridines with different aliphatic aldehydes in mild to good yields.
Abstract
Synth. Commun. 2007, 37, 391
NOVEL PROCEDURE FOR HIGHLY STEREOSELECTIVE SYNTHESIS OF BICYCLIC CYCLOPROPANE-LACTAM WITH CIS-2-ARYL-1-BENZOYL-3,3-DICYANOCYCLOPROPANE AND 2-CYANOMETHYL-1,3-BENZOTHIAZOLE IN WATER
Zhongjiao Ren,1 Weiguo Cao,1,2 Jie Chen,1 and Yeying Lu1
1Department of Chemistry, Shanghai University, Shanghai, China
2State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China
The novel procedure for synthesis of cyclopropyl lactams incorporating benzothiazole structure unit via reaction of cis-2-aryl-1-benzoyl-3,3-dicynocyclopropane and 2-cyanomethyl-1,3-benzothiazole has been achieved.
Abstract
Synth. Commun. 2007, 37, 399
UNEXPECTED MICROWAVE REACTION OF 1,3-DISUBSTITUTED IMIDAZOLIUM SALTS: A NOVEL SYNTHESIS OF 1,3-DISUBSTITUTED IMIDAZOLE-2-THIONES
Xiao-Le Tao, Ming Lei, and Yan-Guang Wang
Department of Chemistry, Zhejiang University, Hangzhou, Zhejiang, China
A microwave-promoted reaction of 1,3-disubstituted imidazolium salts with potassium thioacetate or potassium thiocyanate under solvent-free conditions provided a rapid and efficient synthesis of 1,3-disubstituted imidazole-2-thiones.
Abstract
Synth. Commun. 2007, 37, 409
SIMPLE AND CONVENIENT SYNTHESIS OF 21-THIOALKYLETHER DERIVATIVES OF METHYL 16-PREDNISOLONE CARBOXYLATES
M. Omar F. Khan and Henry J. Lee
College of Pharmacy and Pharmaceutical Sciences, Florida A & M University, Tallahassee, Florida, USA
21-Mesylate of methyl-16-perdnisolonecarboxylate and 9-fluoro-17-dehydro methyl 16-prednisolonecarboxylate were reacted with Na-thioalkoxides to furnish corresponding 21-thioethers.
Abstract
Synth. Commun. 2007, 37, 417
HYDROGENATION OF IMINO-BISNITRILES—SYNTHESIS OF NOVEL TRIAMINES
Raji Sundaramoorthi and Terence P. Keenan
ARIAD Pharmaceuticals Inc., Cambridge, Massachasetts, USA
The hydrogenation of iminonitriles and iminobisnitriles of type 1a–f is a particularly difficult process as the intermediate dieneamines are highly susceptible to addition reactions. A short general method of preparation and purification of 2-aminomethylene-1,3-diamine of type 2a–e by catalytic hydrogenation of iminobisnitriles is described.
Abstract
Synth. Commun. 2007, 37, 425
FACILE SYNTHESIS OF ISODAMASCONE AND ITS ANALOGS
Dinesh W. Rangnekar,1 Vikas S. Kulkarni,1 Prasad V. Ranade,1 and Ram W. Sabnis2
1Dyes Research Laboratory, Institute of Chemical Technology, University of Mumbai, Matunga, Mumbai, India2Ascadia Inc., Eagan, Minnesota, USA
Synthesis of isodamascone and its analogs, the commercially important aroma compounds, have been accomplished from the readily available 1,5,5-trimethyl-2-cyclohexen-1-ol via a short, facile, and simple sequence of reactions in excellent yield.
Abstract
Synth. Commun. 2007, 37, 431
APPLICATION OF POLYMER-SUPPORTED TRIPHENYLPHOSPHINE AND MICROWAVE IRRADIATION TO THE PALLADIUM-CATALYZED CYANATION OF ARYL TRIFLATES
Rajiv R. Srivastava, Andrew J. Zych, David M. Jenkins, Hong-Jun Wang, Zhen-Jia Chen, and David J. Fairfax
Department of Medicinal Chemistry, Albany Molecular Research, Inc., Albany, NY, USA.
Abstract
Synth. Commun. 2007, 37, 439
SYNTHESIS OF IPRATROPIUM BROMIDE–RELATED COMPOUNDS
Irina Tsyskovskaia, Mustapha Kandil, and Yves Beaumier
Pharmascience Inc., Saint-Laurent, Quebec, Canada
Abstract
Synth. Commun. 2007, 37, 447
SYNTHESIS OF A NEW DOXAZOSIN-RELATED COMPOUND
Irina Tsyskovskaia, Mustapha Kandil, and Yves Beaumier
Pharmascience, Saint-Laurent, Quebec, Canada
Abstract
Synth. Commun. 2007, 37, 451
SYNTHESIS OF A NOVEL DISPIROHETEROCYCLIC FRAMEWORK VIA THE REGIOSELECTIVE 1,3-DIPOLAR CYCLOADDITION REACTION OF AZOMETHINE YLIDES
A. R. Suresh Babu and R. Raghunathan
Department of Organic Chemistry, University of Madras, Chennai, India
Abstract
Synth. Commun. 2007, 37, 459
NEW SYNTHESIS OF 2-POLYHFLUOROALKYL SUBSTITUTED 1,4,5,6-TETRAHYDRO-PYRIMIDINES AND 4,5,6,7-TETRAHYDRO-1H-1,3-DIAZEPINES
Alexander V. Rudnichenko and Yuriy G. Shermolovich
Institute of Organic Chemistry, NAS of Ukraine, Kyiv, Ukraine
Abstract
Synth. Commun. 2007, 37, 467
NOVEL ROUTE TO 2-ARYLAPOMORPHINES
Sándor Berényi,1 Attila Sipos,1 Ildikó Szabó,1 and Tamás Kálai2
1Department of Organic Chemistry, University of Debrecen, Debrecen, Hungary
2Institute of Organic and Medicinal Chemistry, University of Pécs, Pécs, Hungary
The synthesis of 2-arylapomorphines (1, 2) has been accomplished using a new method involving a Suzuki-type cross-coupling reaction of 2-bromoapocodeine (8) and arylboronic acids.
Abstract
Synth. Commun. 2007, 37, 473
A NEW FERROCENE-CONTAINING POLYAMIDE PREPARED FROM AN IMPROVED SYNTHESIS OF 1,1′-FERROCENE DICARBONYL CHLORIDE AND FERROCENE-BASED DIAMINE
Muhammad Saif ullah Khan, Asifa Nigar, Mubashir A. Bashir, and Zareen Akhter
Department of Chemistry, Quaid-i-Azam University, Islamabad, Pakistan
Abstract
Synth. Commun. 2007, 37, 483
PREPARATION OF MONOALKYL TEREPHTHALATES: AN OVERVIEW
Elodie-Denise Chenot,1 Dan Bernardi,2 Alain Comel1, and Gilbert Kirsch1
1Laboratoire d'Ingénierie Moléculaire et Biochimie Pharmacologique (LIMBP), Université Paul Verlaine Metz, Metz, France
2Institut de Chimie Organique et Analytique, Université d'Orléans, Orléans, France
This article describes a simple method to convert terephthalic acid into a monoalkyl terephthalate 2 via momohydrolysis of the dialkyl terephthalate 1.
Abstract
Synth. Commun. 2007, 37, 491
ONE‐POT, THREE‐COMPONENT CONDENSATION REACTION IN WATER: AN EFFICIENT AND IMPROVED PROCEDURE FOR THE SYNTHESIS OF PYRAN ANNULATED HETEROCYCLIC SYSTEMS
Ahmad Shaabani, Sima Samadi, and Abbas Rahmati
Department of Chemistry, Shahid Beheshti University, Tehran, Iran.
Abstract
Synth. Commun. 2007, 37, 501
VERSATILE CYCLIZATION OF AMINOANILINO LACTONES: ACCESS TO BENZOTRIAZOLES AND CONDENSED BENZODIAZEPIN-2-THIONES
Lamouri Hammal,1 Samia Bouzroura,1 Chantal André,2 Bellara Nedjar-Kolli,1 and Pascal Hoffmann2
1University of Sciences and Technology Houari Boumediene, Alger, Algeria
2Paul Sabatier University, Toulouse, France
Abstract
Synth. Commun. 2007, 37, 513
SILICA-SUPPORTED BIS (TRIMETHYLSILYL) CHROMATE: OXIDATION OF THIOLS TO THEIR CORRESPONDING DISULFIDES
Majid M. Heavi,1 Fatemeh Derikvanand,1 Hossein A. Oskooie,1 Rahim Hekmat Shoar,1 and Mahmood Tajbakhsh2
1Department of Chemistry, School of Sciences, Azzahra University, Vanak, Tehran, Iran
2Department of Chemistry, Mazandaran University, Babolsar, Iran
An efficient and convenient method for the oxidation of thiols mediated by silica-supported bis (trimethylisilyl) chromate (BTSC) in acetonitrile is reported.
Abstract
Synth. Commun. 2007, 37, 519
NEW ROUTE FOR CONVERSION OF CAMPTOTHECIN TO 7-ETHYLCAMPTOTHECIN AND 7-PROPYLCAMPTOTHECIN
Xin Wang1, Xiaojing Wu2, Ning Cheng2, Huiqing Zhao1, Zhihong Gu1, and Xiang Shen3
1Department of Chemistry, College of Basic Medicine, Anhui Medical University, Hefei, Anhui, China
2School of Chemical Engineering, Hefei University of Technology, Hefei, Anhui, China
3First Affiliated Hospital, Anhui Medical University, Hefei, Anhui, China
In this article, a new route for conversion of camptothecin to 7-ethylcamptothecin and 7-propylcamptothecin is described. Compared with previous reports, the reaction time of the new synthetic route was greatly shortened to 30 min, and the products were obtained in high yield.
