K₅CoW₁₂O₄₀ · 3H₂O: Heterogeneous Catalyst for the Strecker‐Type Aminative Cyanation of Aldehydes and Ketones

Abstract

One‐step synthesis of α‐aminonitriles was successfully carried out by a three‐component condensation of aldehydes or ketones, amines, and potassium cyanide in the presence of a catalytic amount of K₅CoW₁₂O₄₀·3H₂O as an efficient, reusable, and nontoxic catalyst.

Keywords:

• α‐aminonitriles
• polyoxometalates
• potassium cyanide
• Strecker reactions

Acknowledgment

The authors thank the Razi University Research Council and Kermanshah Oil Refining Company for support of this work.