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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 37, 2007 - Issue 15
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Original Articles

Isocyanide‐Based Multicomponent Synthesis of Functionalized 2,6‐Dioxohexahydropyrimidines in 1 M Aqueous Glucose

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Pages 2593-2599 | Received 05 Oct 2006, Published online: 09 Aug 2007
 

Abstract

An effective route to novel 2,6‐dioxohexahydropyrimidines is described. This involves reaction of alkyl isocyanides and dialkyl acetylenedicarboxylates in the presence of N,N′‐dimethylurea in 1M aq. glucose.

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