Efficient and Convenient One‐Pot Synthesis of Phosphoramidates and Phosphates

Abstract

A simple and efficient one‐pot method is described for the synthesis of phosphoramidates/phosphates in excellent yields from dialkylphosphites and trichloroisocyanuric acid in acetonitrile and subsequent treatment with dialkyl amines/alcohols. The procedure is operationally simple, has reduced reaction times, and uses a one‐pot procedure.

Keywords:

• dialkylphosphites
• phosphates
• phosphoramidates
• trichloroisocyanuric acid

Acknowledgments

We thank Shri K. Sekhar, director, DRDE, Gwalior, for his keen interest and encouragement. The authors are also thankful to Mamta Sharma for NMR analysis and D. Pardasani for GC‐MS analysis.