Synthesis of Chiral Benzimidazole‐Pyrrolidine Derivatives and their Application in Organocatalytic Aldol and Michael Addition Reactions

Abstract

An efficient and mild approach for the synthesis of pyrrolidine‐benzimidazoles has been reported. They were further employed for the aldol and Michael addition reactions to afford the corresponding products with good yields and moderate enantioselectivities.

Keywords:

• asymmetric aldol
• benzimidazole
• Michael addition
• organocatalysis
• pyrrolidine

Acknowledgment

We thank the CSIR for financial support under the Task Force Project CMM‐0005. G. Gopi Krishna and C. V. Rajasekhar thank CSIR, India, for the research fellowships.