Sulfamic Acid as a Novel, Efficient, Cost‐Effective, and Reusable Solid Acid Catalyst for the Synthesis of Pyrroles under Solvent‐Free Conditions

Abstract

Paal–Knorr condensation of 2,5‐hexadione with primary amines in the presence of a catalytic amount of sulfamic acid under solvent‐free conditions has been accomplished with an excellent yield. This is a very easy, rapid, and high‐yielding reaction for the synthesis N‐substituted pyrrole derivatives.

Keywords:

• Paal–Knorr reaction
• pyrroles
• solvent‐free conditions
• sulfamic acid