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Abstract
The influence of the substrate structure and concentration on the yield of the Passerini reaction was studied. A new, solvent‐free methodology for a convenient preparation of α‐acyloxyamides 4 was established and compared to the classical methodology. A higher reaction yield was obtained in shorter time, especially in the case of aromatic aldehydes.
Acknowledgment
This work was supported by the grants from the Polish State Committee for Scientific Research, No. PBZ‐KBN‐126/T09/07, PBZ‐MIN‐007/P04/2003.