Abstract
A highly selective synthesis of 2‐substituted benzimidazole derivatives from the reaction of o‐phenylendiamine derivatives and aromatic aldehydes in the presence of an organic salt, NH4OAc, in absolute ethanol is presented. The products were obtained by evaporating the solvent followed by a simple recrystallization with excellent yields.
Acknowledgments
We gratefully acknowledge the support of this work by the Shiraz University Research Council and Shiraz Faculty of Pharmacy. We are also grateful to H. Sajedian Fard his for helpful cooperation.