Synthesis of 4-Hydroxy-3-(1-aryl-2-acetylethyl)-7,8-diaryl-2H-thieno(3,2-h)chromen-2-ones Using Cerium(III) Chloride

Abstract

A new series of 4-hydroxy-3-(1-aryl-2-acetylethyl)-7,8-diaryl-2H-thieno(3,2-h)chromen-2-ones were synthesized in good yields by reacting 4-hydroxy-7,8-diaryl-2H-thieno(3,2-h)chromen-2-ones with various α,β-unsaturated ketones in presence of cerium(III) chloride in acetonitrile.

Keywords:

• Cerium(III) chloride hepta hydrate
• electron-deficient olefins
• 4-hydroxy-7,8-diaryl-2H-thieno(3,2-h)chromen-2-ones
• Michael condensation

ACKNOWLEDGMENT

One of the authors (M. Amaravathi) gratefully acknowledges the Department of Science and Technology, New Delhi, India, for sanctioning Women Scientist Scheme A. We also thank to the National Institute of Technology, Warangal, India, for providing laboratory facilities.