N-Hydroxyphthalimide/Cobalt Acetate, a New Catalytic Oxidative System for the Synthesis of Benzimidazoles: Synthetic Communications: Vol 38, No 20

Synthetic Communications

An International Journal for Rapid Communication of Synthetic Organic Chemistry

Volume 38, 2008 - Issue 20

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Abstract

Benzimidazoles are readily prepared from 1,2-phenylenediamine and an aldehyde using air and catalytic N-hydroxyphthalimide/Co(OAc)₂ as the oxidant. Both electron-donating and electron-withdrawing groups are tolerated.

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N-Hydroxyphthalimide/Cobalt Acetate, a New Catalytic Oxidative System for the Synthesis of Benzimidazoles

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N-Hydroxyphthalimide/Cobalt Acetate, a New Catalytic Oxidative System for the Synthesis of Benzimidazoles

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