Solid-State Synthesis of 1,3-Selenazoles Employing CuPy₂Cl₂ as a Lewis Acid Catalyst

Abstract

1,3-Selenazoles were Synthesized from 3-bromo acetyl coumarin and selenourea in the presence of CuPy₂Cl₂ under solvent-free conditions at ambient temperature. The pure products were identified by spectral data.

Keywords:

• α-Bromo ketone
• CuPy₂Cl₂
• 1,3-selenazole
• selenourea

ACKNOWLEDGMENTS

Financial assistance from University Grants Commission (Rajiv Gandhi National Fellowship) Grant No. F.16–158/2006 (SA-II), New Delhi, is greatly acknowledged.

Notes

Note. Reaction conditions: 3-bromo acetyl coumarin (1 mmol), selenourea (1.2 mmol), and CuPy₂Cl₂ in presence of solvent were stirred at the room temperature for 45 min.

^a All the products were confirmed by ¹H NMR, IR, and mass spectral data.

^b Isolated yields after purification.

^a All the products were confirmed by ¹H NMR, IR, and mass spectral data and compared with those of authentic samples.