Trichloroisocyanuric Acid–KF as an Efficient Reagent for One-Pot Synthesis of Dialkylfluorophosphates from Dialkylphosphites

Abstract

Trichloroisocyanuric acid–KF afforded dialkylfluorophosphates from dialkylphosphites at room temperature through a facile electrophilic–nucleophilic metathesis.

Keywords:

• Dialkylfluorophosphate
• dialkylphosphite
• KF
• trichloroisocyanuric acid

ACKNOWLEDGMENT

We thank Dr. R. Vijayaraghavan, director, DRDE, Gwalior, for his keen interest and encouragement.

Notes

^a isolated yield.

^{b 31}P NMR spectra were recorded at 162 MHz in CDCl₃. All the products gave satisfactory IR, NMR, and GC-MS data compared with authentic samples.

Note. Caution! Dialkylfluorophosphates are highly toxic compounds and should be synthesized by trained persons using an efficient fume hood. Great caution should be exercised especially while distilling them, and residue must be properly decontaminated by using 20% alkali solution.