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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 38, 2008 - Issue 23
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Original Articles

Brine-Mediated Efficient Benzoylation of Primary Amines and Amino Acids

, &
Pages 4068-4075 | Received 08 Apr 2008, Published online: 31 Oct 2008
 

Abstract

Benzoylation of primary amines and amino acids is efficiently carried out in a brine solution using a stoichiometric amount of benzoyl chloride followed by trituration with aqueous saturated bicarbonate solution.

ACKNOWLEDGMENT

We are thankful to D. K. Neogi, director, School of Tropical Medicine, for his interest in the work. We are also thankful to the Council of Scientific and Industrial Research (CSIR), New Delhi, India, for providing a junior research fellowship to one of the authors (S. C.).

Notes

a Products were characterized by their spectral data.

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