Potassium Dodecatungsto Cobaltate Trihydrate: A New Heterogeneous Catalyst for the Synthesis of Homoallylic Alcohols and Amines

Abstract

A simple and efficient procedure has been developed for one-pot synthesis of homoallylic alcohols and amines in good to excellent yields using a variety of aldehydes, amines, and allyltributylstannane in the presence of a catalytic amount of potassium dodecatungsto cobaltate trihydrate (K₅CoW₁₂O₄₀ · 3H₂O) as a heterogeneous catalyst at room temperature. The catalyst exhibited remarkable reusability.

Keywords:

• Allyltributylstannane
• homoallylic alcohols
• homoallylic amines
• potassium dodecatungsto cobaltate trihydrate
• reusability

ACKNOWLEDGMENT

S. A. thanks Council of Scientific and Industrial Research, New Delhi, for financial assistance, and authors thank the head, Organic Chemistry Division II, and director, Indian Institute of Chemical Technology, Hyderabad, for their constant encouragement and support.

Notes

^a All products were characterized by ¹H NMR, ¹³C NMR, IR, and mass spectroscopy.

^b Isolated and unoptimized yields.

^a All products were characterized by ¹H NMR, ¹³C NMR, IR, and mass spectroscopy.

^b Isolated and unoptimized yields.