Practical, Ecofriendly, and Chemoselective Method for the Synthesis of 2-Aryl-1-arylmethyl-1H-benzimidazoles Using Amberlite IR-120 as a Reusable Heterogeneous Catalyst in Aqueous Media

Abstract

A simple, efficient, and environmentally benign method has been developed for the exclusive formation of biologically significant 2-aryl-1-arylmethyl-1H-benzimidazoles under the heterogeneous catalysis of Amberlite IR-120 in aqueous media in excellent yields. The catalyst is recyclable without loss of activity.

Keywords:

• Amberlite IR-120
• aqueous media
• chemoselective
• 1,2-disubstituted benzimidazole
• heterogeneous catalysis

ACKNOWLEDGMENT

The authors acknowledge the director of the Northeast Institute of Science and Technology, Jorhat, for his help. Also, S. D. S. is grateful to Council of Scientific and Industrial Research (CSIR), New Delhi, for the senior research fellowship.

Notes

^a Isolated yield.

^b Stirring at 25–30 °C.

^a Isolated yield.

^b Stirring at 25–30 °C.