Cellulose Sulfuric Acid: An Efficient Biodegradable and Recyclable Solid Acid Catalyst for the One-Pot Synthesis of 3,4-Dihydropyrimidine-2(1H)-ones

Abstract

Biosupported cellulose sulfuric acid has been found to be an efficient solid acid catalyst for the one-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones. The advantages of this method are avoidance of harsh reaction conditions, ecofriendly chemistry, operational simplicity, high yield, and reusable catalyst.

Keywords:

• Biginelli reaction
• biosupported catalyst
• cellulose sulfuric acid (CSA)
• 3,4-dihydropyrimidin-2(1H)-ones
• one-pot synthesis

Notes

^a Isolated yield.

^a Isolated yield.

^a Yields refer to pure solid products; all products were reported in the literature and were characterized by comparison of their physical and spectral data with those previously reported.