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Abstract
A novel and convenient synthesis of rivastigmine has been reported. This procedure provides high yield and excellent enantiomeric excess (100% ee) starting from the diastereromerically pure (S)-1-(3-methoxyphenyl)-N-[(S)-1-phenylethyl] ethanamine.
ACKNOWLEDGMENTS
We are grateful to the Social Development Foundation of Shanghai (No. 05DZ19348) for financial support.