Solid-Phase Synthesis of N-Aryl Succinimides

Abstract

A new method upon adopting a solid-phase strategy for synthesis of N-aryl succinimides is described here, using the silica-bound benzoyl chloride (SBBC) as dehydrating agent in reaction with N-arylsuccinamic acids. The main advantage of this method is the recyclability of SBBC.

Keywords:

• Silica-bound benzoyl chloride
• solid-phase synthesis
• succinimide

ACKNOWLEDGMENT

We gratefully acknowledge financial support from the Research Council of the University of Guilan.