Simple System for Cleavage of Alkene C–C Bond Using Aqueous Sodium Paraperiodate

Abstract

A simple and mild method for direct conversion of alkenes to corresponding aldehydes has been developed using sodium paraperiodate (Na₃H₂IO₆) in water. The reagent was found to give excellent yields of corresponding aldehydes.

Keywords:

• Aldehyde
• C–C double bond
• sodium paraperiodate
• water

ACKNOWLEDGMENT

We gratefully acknowledge the University Grants Commission, India, for financial support under the scheme of a UGC major research project.

Notes

^a Typically, Na₃H₂IO₆ (12 mmol) reacted with substrate (10 mmol) in water (25 mL) at 70°C.

^b Starting compounds were prepared by standard literature procedures.

^c Isolated yields after column chromatography and structure was confirmed by comparison of IR and ¹H NMR with those of authentic materials.

^d NR: no reaction.