Abstract
Molecular iodine is found to catalyze the condensation of acetophenones with various aromatic aldehydes to prepare chalcones.
ACKNOWLEDGMENTS
The Authors are grateful to the director, CDRI, Lucknow, India, for constant encouragement for the drug development program, SAIF for 300-MHz NMR and mass spectral data, and S. P. Singh for technical support. J. N. R. and A. K. thank the University Grants Commission and the Council of Scientific and Industrial Research, New Delhi, India, respectively for financial support.
Notes
a All the products were characterized 1H NMR, 13C NMR, and mass spectroscopy.
b Isolated yields after column chromatography.
Part 4 in the series Studies on Novel Synthetic Methodologies. CDRI Communication No. 7418.