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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 39, 2009 - Issue 13
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Original Articles

Triton B–Mediated Mild, Convenient, and Efficient Method for the Selective Alkylation of Cyclic Secondary Amines and Thiols

, &
Pages 2297-2303 | Received 21 Aug 2008, Published online: 01 Jun 2009
 

Abstract

Alkylation of cyclic secondary amines, thiols, and pyridazinones has been demonstrated with alkyl halides using Triton B as base and reaction medium.

ACKNOWLEDGMENTS

B. C. K. R. and P. R. G. thank the Council of Scientific and Industrial Research–University Grants Commission for the award of a fellowship and Dr. J. S. Yadav, director, Indian Institute of Chemical Technology, for his support and encouragement.

Notes

a All the products exhibited physical and spectral (NMR, mass, IR) properties in accordance with the assigned structure.

b All reactions are carried out at rt only.

c Isolated yield.

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