Advanced search
Publication Cover
Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 39, 2009 - Issue 13
Submit an article Journal homepage
1,029
Views
64
CrossRef citations to date
0
Altmetric
Original Articles

A Simple and Convenient One-Pot Synthesis of Benzimidazole Derivatives Using Cobalt(II) Chloride Hexahydrate as Catalyst

Abu T. Khan Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati, IndiaCorrespondence[email protected]
,
Tasneem Parvin Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati, India
&
Lokman H. Choudhury Department of Basic Sciences and Social Sciences, Northeastern Hill University, Shillong, India
Pages 2339-2346 | Received 12 Sep 2008, Published online: 01 Jun 2009
 
Sample our Physical Sciences journals, sign in here to start your FREE access for 14 days

Abstract

A simple and efficient method for the convenient synthesis of 2-arylbenzimidazole has been described on reaction with o-phenylenediamine and various aromatic aldehydes using cobalt(II) chloride hexahydrate as a catalyst. The method is cost-effective, high-yielding, clean, and selective.

ACKNOWLEDGMENTS

T. P. is thankful to the Indian Institute of Technology Guwahati (IITG) for her research fellowship. Authors are also grateful to the director, IITG, for providing the general facilities to carry out the work.

Notes

a Products were characterized by recording IR, 1H NMR, and 13C NMR spectra and elemental analysis.

b Isolated yield.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related Research Data

Eco-Friendly Synthesis of 2-Substituted Benzimidazoles Using Air as the Oxidant
Source: CSIRO Publishing
Medical implications of benzimidazole derivatives as drugs designed for targeting DNA and DNA associated processes.
Source: Bentham Science Publishers Ltd.
Iron(III) chloride-catalyzed convenient one-pot synthesis of β-acetamido carbonyl compounds
Source: Elsevier BV
Magnetic Bisphosphonic Acid Nanohybrid Catalyzed Heterogeneous Synthesis of Heterocylcles
Source: Wiley
Metal catalyst free one-pot synthesis of 2-arylbenzimidazoles from α-aroylketene dithioacetals
Source: Royal Society of Chemistry (RSC)
Immobilized Ni-Schiff-base metal complex on MCM-41 as a heterogeneous catalyst for the green synthesis of benzimidazole derivatives using glycerol as a solvent
Source: Springer Science and Business Media LLC
Metallovesicles as smart nanoreactors for green catalytic synthesis of benzimidazole derivatives in water
Source: Royal Society of Chemistry (RSC)
Chitosan-supported Fe3O4 nanoparticles: a magnetically recyclable heterogeneous nanocatalyst for the syntheses of multifunctional benzimidazoles and benzodiazepines
Source: Royal Society of Chemistry (RSC)
A simple and metal-free one-pot synthesis of 2-substituted-1 H -4-carboxamide benzimidazole using 3,6-di(pyridin-2-yl)-1,2,4,5-tetrazine(PYTZ) as catalyst
Source: Springer Science and Business Media LLC
Simple, Efficient, and Applicable Route for Synthesis of 2-Aryl(Heteroaryl)-Benzimidazoles at Room Temperature Using Copper Nanoparticles on Activated Carbon as a Reusable Heterogeneous Catalyst
Source: Springer Science and Business Media LLC
A Simple and Efficient One-Pot Synthesis of 2-Substituted Benzimidazoles.
Source: Wiley
Synthèse chimiosélective des benzimidazoles sur silice traitée par le chlorure du thionyle
Source: Elsevier BV
Selective Synthesis of 2‐Aryl‐1‐arylmethyl‐1H‐1,3‐benzimidazoles in Water at Ambient Temperature.
Source: Wiley
Design, Microwave‐Assisted Synthesis, and Spasmolytic Activity of 2‐(Alkyloxyaryl)‐1H‐benzimidazole Derivatives as Constrained Stilbene Bioisosteres.
Source: Wiley
Efficient (bromodimethyl)sulfonium bromide mediated synthesis of benzimidazoles
Source: Elsevier BV
Zirconocene catalyzed synthesis of 2-substituted benzimidazole derivatives
Source: Springer Science and Business Media LLC
Mesoporous silica supported ytterbium as heterogeneous catalyst
Source: Wiley
Preparation of tin-modified mono-ammonium phosphate fertilizer and its application as heterogeneous catalyst in the benzimidazoles and benzothiazoles synthesis
Source: Springer Science and Business Media LLC
A Simple and Efficient Procedure for the Synthesis of Benzimidazoles Using Air as the Oxidant.
Source: Wiley
Synthesis of benzimidazoles in high-temperature water
Source: Royal Society of Chemistry (RSC)
Mild and Highly Efficient Method for the Synthesis of 2-Arylbenzimidazoles and 2-Arylbenzothiazoles
Source: American Chemical Society (ACS)
Electrochemical Synthesis of Benzazoles from Alcohols and o-Substituted Anilines with a Catalytic Amount of CoII Salt
Source: Wiley
An Efficient and One-Pot Synthesis of Imidazolines and Benzimidazoles via Anaerobic Oxidation of Carbon—Nitrogen Bonds in Water.
Source: Wiley
POCl3-mediated synthesis of 2-substituted benzimidazolyl-coumarin, benzimidazolyl-indole, and styrylbenzimidazole derivatives
Source: (:unav)
A new “traceless” solid-phase synthesis strategy: Synthesis of a benzimidazole library
Source: Elsevier BV

Linking provided by 

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.