Abstract
A versatile and efficient route to 3-amino-1-aryl-9H-fluorene-2,4-dicarbonitrile via multicomponent reactions of 1-indanone, aromatic aldehydes, and malononitrile under solvent-free conditions using NaOH as the catalyst is described. This method provides several advantages over alternative procedures such as mild, solvent-free conditions at ambient temperature and direct isolation of the products in good yields.
ACKNOWLEDGMENTS
We thank the Natural Science Foundation of Jiangsu Education Department (No. 08KJB150017) and the PeiYu Foundation (No. 07PYL06) of Xuzhou Normal University for financial support.