Catalytic Effects in Baylis–Hillman Reactions of Chromone-3-carbaldehydes with Acrylonitrile and Methyl Acrylate

Abstract

The effects of various catalysts, the solvent system, and the temperature on the efficiency and chemoselectivity of reactions of a series of chromone-3-carbaldehydes with acrylonitrile and methyl acrylate are discussed.

Keywords:

• Baylis–Hillman catalysts
• chromone-3-carbaldehydes
• solvent systems

ACKNOWLEDGMENTS

The authors thank the Medical Research Council of South Africa (MRC) for a bursary (to D. M. M.) and Rhodes University, the National Research Foundation (NRF), and the MRC for generous financial support.

Notes

^a Yields in parentheses.

Chromone Studies, Part 16.