Synthesis of 3-Methyl-2,6-dimethylbicyclo[3.3.1]nonane-exo-2,exo-6-diol

Na Yang Department of Medicinal Chemistry, School of Pharmacy, East China University of Science and Technology, Shanghai, China

Fei Wu Department of Medicinal Chemistry, School of Pharmacy, East China University of Science and Technology, Shanghai, China

Jiabin Gao Department of Medicinal Chemistry, School of Pharmacy, East China University of Science and Technology, Shanghai, China

Xiaoyan Luo Department of Medicinal Chemistry, School of Pharmacy, East China University of Science and Technology, Shanghai, China

Weimin Yue Department of Medicinal Chemistry, School of Pharmacy, East China University of Science and Technology, Shanghai, ChinaCorrespondence[email protected]

Abstract

In this article, a new 2,6-dimethylbicyclo[3.3.1]nonane-exo-2, exo-6-diol derivative was designed and synthesized. First, the precursor compound (8) was prepared. Key intermediate dione compounds were obtained by reaction with iodomethane followed by hydrolysis and decarboxylation. Finally, methylation of the mixture of compounds 10a and 10b resulted in the formation of the title compound (5).

Keywords:

ACKNOWLEDGMENTS

This research was sponsored by Shanghai Pujiang Program (No. 06PJ14029).

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Synthesis of 3-Methyl-2,6-dimethylbicyclo[3.3.1]nonane-exo-2,exo-6-diol

Information for

Open access

Opportunities

Help and information

Synthesis of 3-Methyl-2,6-dimethylbicyclo[3.3.1]nonane-exo-2,exo-6-diol

Abstract

ACKNOWLEDGMENTS

Reprints and Corporate Permissions

Academic Permissions

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date

Your download is now in progress and you may close this window

Login or register to access this feature