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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 40, 2010 - Issue 3
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Original Articles

Efficient Thiocyanation of Indoles Using Para-Toluene Sulfonic Acid

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Pages 337-341 | Received 27 Dec 2008, Published online: 06 Jan 2010
 

Abstract

Treatment of indoles with ammonium thiocyanate in the presence of para-toluene sulfonic acid afforded the corresponding 3-thiocyano indoles at room temperature in excellent yields.

ACKNOWLEDGMENTS

The authors thank the Council of Scientific and Industrial Research and the University Grants Commission, New Delhi, India, for financial assistance.

Notes

a The structures of the products were settled from their spectral (IR, 1H NMR, and MS) data.

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