Synthesis of Isobenzofuran-1(3H)-ones with the Aid of Silica-Supported Preyssler Nanoparticles

Abstract

Silica-supported Preyssler nanoparticles appear to be a new and efficient solid acid catalyst for an economical, and environmentally benign one-pot synthesis of 3-substituted phthalides.

Keywords:

• Isobenzofuran-1(3H)-ones
• one-pot synthesis
• phthalaldehydic acid
• silica-supported Preyssler nanoparticles
• solvent-free condition

ACKNOWLEDGMENT

The authors are thankful to Azzahra Research Council for partial financial support.

Notes

^a Yields were analyzed by GC.

^a Reaction conditions: phthalaldehydic acid (0.8 mmol), ketone (1 mmol), nano-structured Preyssler supported on silica (0.03 mmol), 110°C, 6h.

^b GC yields, based on phthalaldehydic acid.