Three-Component Reaction of 5,5-Dimethylcyclohexan-1,3-dione, Aromatic Aldehydes, and Acetonitrile in the Presence of Chlorosulfonic Acid Forming N-[(2-Hydroxy-4,4-dimethyl-6-oxocyclohexene-1-yl)-aryl-methyl]-acetamides

Mohammad Anary-Abbasinejad Department of Chemistry, Islamic Azad University, Yazd Branch, Yazd, IranCorrespondence[email protected]

Alireza Hassanabadi Department of Chemistry, Islamic Azad University, Yazd Branch, Yazd, Iran

Khadijeh Charkhati Department of Chemistry, Islamic Azad University, Yazd Branch, Yazd, Iran

Abstract

A three-component reaction between 5,5-dimethylcyclohexan-1,3-dione (dimedone), aromatic aldehydes, and acetonitrile in the presence of chlorosulfonic acid afforded N-[(2-hydroxy-4,4-dimethyl-6-oxocyclohexene-1-yl)-aryl-methyl]-acetamides in good yields. The temperature-dependent ¹H NMR of one of the products has been investigated.

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Three-Component Reaction of 5,5-Dimethylcyclohexan-1,3-dione, Aromatic Aldehydes, and Acetonitrile in the Presence of Chlorosulfonic Acid Forming N-[(2-Hydroxy-4,4-dimethyl-6-oxocyclohexene-1-yl)-aryl-methyl]-acetamides

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Three-Component Reaction of 5,5-Dimethylcyclohexan-1,3-dione, Aromatic Aldehydes, and Acetonitrile in the Presence of Chlorosulfonic Acid Forming N-[(2-Hydroxy-4,4-dimethyl-6-oxocyclohexene-1-yl)-aryl-methyl]-acetamides

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