Triton B–Assisted, Efficient, and Convenient Synthesis of 3-Indolyl-3-hydroxy Oxindoles in Aqueous Medium

Abstract

An efficient and convenient synthesis of 3-indolyl-3-hydroxy oxindole is described by the reaction of isatin with indole in the presence of Triton B in an aqueous medium.

Keywords:

• Aqueous medium
• indole
• isatin
• oxindole
• Triton B

ACKNOWLEDGMENTS

D. A., P. R. G., and B. C. K. R. thank the Council of Scientific and Industrial Research for the award of a fellowship and J. S. Yadav, director, Indian Institute of Chemical Technology, for his support and encouragement.

Notes

^a All the products exhibited physical and spectral (NMR, mass, IR) properties in accordance with the assigned struture.

^b Isolated.