Selective Decarboxylation: A Facile Synthesis of 3-Pyridinecarboxylic Acid Derivative

Junhua Wang Institute of Marine Material Science and Engineering, Shanghai Maritime University, Shanghai, ChinaCorrespondence[email protected]

Honglin Wang School of Chemistry, Yunnan University, Kunming, China

Hongmin Ren Institute of Marine Material Science and Engineering, Shanghai Maritime University, Shanghai, China

Lihua Dong Institute of Marine Material Science and Engineering, Shanghai Maritime University, Shanghai, China

Abstract

A convenient synthesis of 5-trifluoromethyl-3-pyridinecarboxylic acid was developed, involving palladium-catalyzed carbonylation, hydrolysis, and decarboxylation. This novel route features inexpensive starting material and easy operations.

Keywords:

ACKNOWLEDGMENTS

We thank the Natural Science Fund of China (No. 20772142) and Shanghai Maritime University Fund (No. 2009156) for financial support.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Selective Decarboxylation: A Facile Synthesis of 3-Pyridinecarboxylic Acid Derivative

Information for

Open access

Opportunities

Help and information

Selective Decarboxylation: A Facile Synthesis of 3-Pyridinecarboxylic Acid Derivative

Abstract

ACKNOWLEDGMENTS

Reprints and Corporate Permissions

Academic Permissions

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date

Your download is now in progress and you may close this window

Login or register to access this feature